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2023

Remodeling the cellular stress response for enhanced genetic code expansion in mammalian cells

10.1038/s41467-023-42689-2

Mikhail E. Sushkin, Christine Koehler & Edward A. Lemke

2023
Bioconjugation/ADC
2023
2023

Genetic Code Expansion for Site-Specific Labeling of Antibodies with Radioisotopes

10.1021/acschembio.2c00634

Christine Koehler*, Paul F Sauter* , Benedikt Klasen, Christopher Waldmann, Stefanie Pektor, Nicole Bausbacher, Edward A Lemke , Matthias Miederer

2023
Bioconjugation/ADC
2023
2021

Synthesis and Evaluation of Novel Ring-Strained Noncanonical Amino Acids for Residue-Specific Bioorthogonal Reactions in Living Cells.

10.1002/chem.202100322

Reinkemeier CD, Koehler C, Sauter PF, Shymanska NV, Echalier C, Rutkowska A, Will DW, Schultz C, Lemke EA

2021
Bioconjugation/ADC
Before 2022
2020

Inducible Genetic Code Expansion in Eukaryotes.

10.1002/cbic.202000338

Koehler C, Estrada Girona G, Reinkemeier CD, Lemke EA.

2020
Bioconjugation/ADC
Before 2022
2019

Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes

10.1126/science.aaw2644

Reinkemeier CD, Girona GE, Lemke EA

2019
Bioconjugation/ADC
Before 2022
2018

Single-Cell Droplet Microfluidic Screening for Antibodies Specifically Binding to Target Cells

doi: 10.1016/j.celrep.2018.01.071

Shembekar N, Hu H, Eustace D, Merten CA

2018
Microfluidics/Screening
Before 2022
2018

MultiBacTAG-Genetic Code Expansion Using the Baculovirus Expression System in Sf21 Cells

10.1007/978-1-4939-7574-7_19

Christine Koehler, Edward A Lemke

2018
Bioconjugation/ADC
Before 2022
2017

Microfluidic train station: highly robust and multiplexable sorting of droplets on electric rails

10.1039/c6lc01544a

Frenzel D and Merten CA

2017
Microfluidics/Screening
Before 2022
2017

Single-Virus Droplet Microfluidics for High-Throughput Screening of Neutralizing Epitopes on HIV Particles

10.1016/j.chembiol.2017.05.009

Chaipan C, Pryszlak A, Dean H, Benes V, Griffiths AD, Merten CA

2017
Microfluidics/Screening
Before 2022
2016

Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics

10.1039/c6lc00249h

Shembekar N, Chaipan C, Utharala R, Merten CA

2016
Microfluidics/Screening
Before 2022
2016

Genetic code expansion for multiprotein complex engineering

10.1038/nmeth.4032

Koehler C, Sauter PF, Wawryszyn M, Estrada Girona G, Gupta K, Landry JJM, Hsi‐Yang Fritz M, Radic K, Hoffmann J-E, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt‐Bergner P, Pruneri G, Gyenesei A, Schultz C, Biskup MB, Besir H, Benes V, Rappsilber J, Jechlinger M, Korbel JO, Berger I, Braese S, Lemke EA

2016
Bioconjugation/ADC
Before 2022
2015

Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.

10.1002/chem.201501647

Jan-Erik Hoffmann, Tilman Plass, Ivana Nikić, Iker Valle Aramburu, Christine Koehler, Hartmut Gillandt, Edward A Lemke, Carsten Schultz

2015
Bioconjugation/ADC
Before 2022
2015

Efficient cell pairing in droplets using dual-color sorting

10.1039/c5lc00686d

Hongxing Hu, David Eustace, Christoph A Merten

2015
Microfluidics/Screening
Before 2022
2014

Minimal tags for rapid dual-color live-cell labeling and super-resolution microscopy

10.1002/anie.201309847

Ivana Nikić , Tilman Plass, Oliver Schraidt, Jędrzej Szymański, John A G Briggs, Carsten Schultz, Edward A Lemke

2014
Bioconjugation/ADC
Before 2022
2012

Functional single-cell hybridoma screening using droplet-based microfluidics

10.1073/pnas.1204514109

Bachir El Debs, Ramesh Utharala, Irina V Balyasnikova, Andrew D Griffiths, Christoph A Merten

2012
Microfluidics/Screening
Before 2022
2012

Click strategies for single-molecule protein fluorescence.

10.1021/ja210587q

Sigrid Milles, Swati Tyagi, Niccolò Banterle, Christine Koehler, Virginia VanDelinder, Tilman Plass, Adrian P Neal, Edward A Lemke

2012
Bioconjugation/ADC
Before 2022
2012

Amino Acids for Diels-Alder Reactions in Living Cells

10.1002/anie.201108231

Plass T, Milles S, Koehler C, Szymanski J. Mueller R, Wieβler M, Schultz C, Lemke EA

2012
Bioconjugation/ADC
Before 2022
2011

Genetically encoded copper-free click chemistry

10.1002/anie.201008178

Plass T, Milles S, Koehler C, Schultz C, Lemke EA

2011
Bioconjugation/ADC
Before 2022
2008

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

10.1016/j.chembiol.2008.04.004

Clausell-Tormos J, LiebJenifer Clausell-Tormos 1, Diana Lieber, Jean-Christophe Baret, Abdeslam El-Harrak, Oliver J Miller, Lucas Frenz, Joshua Blouwolff, Katherine J Humphry, Sarah Köster, Honey Duan, Christian Holtze, David A Weitz, Andrew D Griffiths, Christoph A Mertener D, Baret JC, El-Harrak A, Frenz L, Blouwolff J., Katherine J.Humphry KJ, Köster S, Duan H, Holtze C, Weitz DA, Griffiths AD, Merten CA

2008
Microfluidics/Screening
Before 2022